The Kidney Contains Ontogenetically Distinct Dendritic Cell and Macrophage Subtypes throughout Development That Differ in Their Inflammatory Properties
Author(s) -
Natallia Salei,
Stephan Rambichler,
Johanna Salvermoser,
Nikos E. Papaioannou,
R. Schuchert,
Dalia Pakalniškytė,
Na Li,
Julian A. Marschner,
Julia Lichtnekert,
Christopher Stremmel,
Filippo M. Cernilogar,
Melanie Salvermoser,
Barbara Walzog,
Tobias Straub,
Gunnar Schotta,
HansJoachim Anders,
Christian Schulz,
Barbara U. Schraml
Publication year - 2020
Publication title -
journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.451
H-Index - 279
eISSN - 1533-3450
pISSN - 1046-6673
DOI - 10.1681/asn.2019040419
Subject(s) - biology , kidney , dendritic cell , immune system , embryonic stem cell , macrophage , immunology , population , flow cytometry , progenitor cell , microbiology and biotechnology , stem cell , medicine , in vitro , endocrinology , genetics , environmental health , gene
Mononuclear phagocytes (MPs), including macrophages, monocytes, and dendritic cells (DCs), are phagocytic cells with important roles in immunity. The developmental origin of kidney DCs has been highly debated because of the large phenotypic overlap between macrophages and DCs in this tissue.
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