Open AccessSolving Baroreceptor Mystery: Role of PIEZO Ion Channels
Author(s) -
Suzanne D. Burke,
Jens Jordan,
David G. Harrison,
S. Ananth Karumanchi
Publication year - 2019
Publication title -
journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.451
H-Index - 279
eISSN - 1533-3450
pISSN - 1046-6673
DOI - 10.1681/asn.2019020160
Subject(s) - baroreceptor , ion channel , ion , neuroscience , medicine , biophysics , cardiology , chemistry , psychology , biology , heart rate , blood pressure , receptor , organic chemistry
Baroreceptors are pressure sensors on specialized neurons that specifically detect stretch within arterial walls, which occurs when BP increases. When baroreceptors are stretched, they transmit afferent (sensory) signals to the nucleus tractus solitarii in the medulla. These signals inhibit
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