A Randomized Trial of Magnesium Oxide and Oral Carbon Adsorbent for Coronary Artery Calcification in Predialysis CKD | Zendy

Yusuke Sakaguchi | Zendy; Takayuki Hamano | Zendy; Yoshitsugu Obi | Zendy; Chikako Monden | Zendy; Tatsufumi Oka | Zendy; Satoshi Yamaguchi | Zendy; Isao Matsui | Zendy; Nobuhiro Hashimoto | Zendy; Ayumi Matsumoto | Zendy; Karin Shimada | Zendy; Yoshitsugu Takabatake | Zendy; Atsushi Takahashi | Zendy; Jun-Ya Kaimori | Zendy; Toshiki Moriyama | Zendy; Ryohei Yamamoto | Zendy; Masaru Horio | Zendy; Kōichi Yamamoto | Zendy; Ken Sugimoto | Zendy; Hiromi Rakugi | Zendy; Yoshitaka Isaka | Zendy

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A Randomized Trial of Magnesium Oxide and Oral Carbon Adsorbent for Coronary Artery Calcification in Predialysis CKD

Author(s) -

Yusuke Sakaguchi,

Takayuki Hamano,

Yoshitsugu Obi,

Chikako Monden,

Tatsufumi Oka,

Satoshi Yamaguchi,

Isao Matsui,

Nobuhiro Hashimoto,

Ayumi Matsumoto,

Karin Shimada,

Yoshitsugu Takabatake,

Atsushi Takahashi,

Jun-Ya Kaimori,

Toshiki Moriyama,

Ryohei Yamamoto,

Masaru Horio,

Kōichi Yamamoto,

Ken Sugimoto,

Hiromi Rakugi,

Yoshitaka Isaka

Publication year - 2019

Publication title -

journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.451

H-Index - 279

eISSN - 1533-3450

pISSN - 1046-6673

DOI - 10.1681/asn.2018111150

Subject(s) - medicine , randomized controlled trial , kidney disease , diabetes mellitus , coronary artery disease , gastroenterology , endocrinology

Developing strategies for managing coronary artery calcification (CAC) in patients with CKD is an important clinical challenge. Experimental studies have demonstrated that magnesium inhibits vascular calcification, whereas the uremic toxin indoxyl sulfate aggravates it.

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