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The RNA-Protein Interactome of Differentiated Kidney Tubular Epithelial Cells
Author(s) -
Michael Ignarski,
Constantin Rill,
Rainer Kaiser,
Madlen Kaldirim,
René Neuhaus,
Reza Esmaillie,
Xinping Li,
Corinna Klein,
Katrin Bohl,
Maike Petersen,
Christian K. Frese,
Martin Höhne,
Ilian Atanassov,
Markus M. Rinschen,
Katja Höpker,
Bernhard Schermer,
Thomas Benzing,
Christoph Dieterich,
Francesca Fabretti,
RomanUlrich Müller
Publication year - 2019
Publication title -
journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.451
H-Index - 279
eISSN - 1533-3450
pISSN - 1046-6673
DOI - 10.1681/asn.2018090914
Subject(s) - rna binding protein , biology , interactome , proteome , microbiology and biotechnology , rna , translational regulation , messenger rna , translation (biology) , computational biology , regulation of gene expression , genetics , gene
RNA-binding proteins (RBPs) are fundamental regulators of cellular biology that affect all steps in the generation and processing of RNA molecules. Recent evidence suggests that regulation of RBPs that modulate both RNA stability and translation may have a profound effect on the proteome. However, regulation of RBPs in clinically relevant experimental conditions has not been studied systematically.

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