T Cells Play a Causal Role in Diastolic Dysfunction during Uremic Cardiomyopathy
Author(s) -
Pamela D. Winterberg,
Jennifer Robertson,
Michael Kelleman,
Roshan George,
Mandy L. Ford
Publication year - 2019
Publication title -
journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.451
H-Index - 279
eISSN - 1533-3450
pISSN - 1046-6673
DOI - 10.1681/asn.2017101138
Subject(s) - medicine , heart failure , cardiomyopathy , diastole , cardiology , left ventricular hypertrophy , blood pressure
Uremic cardiomyopathy, characterized by left ventricular hypertrophy, diastolic dysfunction, and impaired myocardial strain, contributes to increased cardiovascular mortality in patients with CKD. Emerging evidence suggests a pathogenic role for T cells during chronic heart failure.
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