Open AccessThe Pas de Trois of Vitamin D, FGF23, and PTH
Author(s) -
Tally NavehMany,
Justin Silver
Publication year - 2016
Publication title -
journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.451
H-Index - 279
eISSN - 1533-3450
pISSN - 1046-6673
DOI - 10.1681/asn.2016090944
Subject(s) - endocrinology , medicine , parathyroid hormone , fibroblast growth factor 23 , klotho , secondary hyperparathyroidism , uremia , phex , chemistry , hyperparathyroidism , vitamin d and neurology , biology , kidney , calcium , rickets
There is a remarkable interaction among the factors that increase fibroblast growth factor 23 (FGF23) transcription in the osteocyte and osteoblast, where they are individually and collectively essential for the fine tuning of FGF23 expression and secretion. Serum levels of the three hormones, PTH,
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