Open AccessCould Autophagic Exhaustion Be a Final Common Pathway for Podocytopathy in FSGS?
Author(s) -
Manjeri A. Venkatachalam
Publication year - 2014
Publication title -
journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.451
H-Index - 279
eISSN - 1533-3450
pISSN - 1046-6673
DOI - 10.1681/asn.2014090919
Subject(s) - podocyte , pathology , nephron , focal segmental glomerulosclerosis , medicine , disease , pathogenesis , synaptopodin , kidney , glomerulonephritis , proteinuria
Among renal syndromes caused by glomerular disorders, FSGS continues to pose the most challenges in understanding its pathogenesis and therefore, in arriving at mechanism-based approaches for its treatment. The extraordinary diversity of genetic etiologies linked to primary FSGS, the sizable number
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