Apolipoprotein L1 and the Genetic Basis for Racial Disparity in Chronic Kidney Disease | Zendy

Susan E. Quaggin | Zendy; Alfred L. George | Zendy

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Apolipoprotein L1 and the Genetic Basis for Racial Disparity in Chronic Kidney Disease

Author(s) -

Susan E. Quaggin,

Alfred L. George

Publication year - 2011

Publication title -

journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.451

H-Index - 279

eISSN - 1533-3450

pISSN - 1046-6673

DOI - 10.1681/asn.2011090932

Subject(s) - kidney disease , focal segmental glomerulosclerosis , nephropathy , disease , linkage disequilibrium , medicine , single nucleotide polymorphism , genetics , biology , bioinformatics , kidney , endocrinology , glomerulonephritis , diabetes mellitus , gene , genotype

Persons of African ancestry living in the United States carry a disproportionate burden of chronic kidney disease (CKD). Compared with Americans of European ancestry, African Americans have an approximately fourfold greater life time risk of ESRD and, on average, require initiation of renal

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