Open AccessGlomerular Filtration Barrier and Molecular Segregation
Author(s) -
Steven J. Harper,
David O. Bates
Publication year - 2010
Publication title -
journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.451
H-Index - 279
eISSN - 1533-3450
pISSN - 1046-6673
DOI - 10.1681/asn.2010101071
Subject(s) - slit diaphragm , glycocalyx , chemistry , renal function , basement membrane , podocyte , biophysics , glomerular basement membrane , membrane , filtration (mathematics) , endothelium , kidney , medicine , microbiology and biotechnology , glomerulonephritis , biology , biochemistry , proteinuria , statistics , mathematics
The normal phenotype of the glomerular filtration barrier (GFB) and the mechanisms that underlie it have intrigued physiologists, microvascular biologists, and renal physicians for decades, especially because, in health, the multilayered barrier differentially restricts the passage of molecules of
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