Open AccessBreaking Down the Barrier
Author(s) -
Scott J. Harvey,
Jeffrey H. Miner
Publication year - 2007
Publication title -
journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.451
H-Index - 279
eISSN - 1533-3450
pISSN - 1046-6673
DOI - 10.1681/asn.2007010086
Subject(s) - ferritin , peroxidase , selectivity , dextran , chemistry , materials science , biochemistry , enzyme , catalysis
The glomerular capillary wall is thought to function as both a size- and charge-selective barrier. The concept of charge selectivity emerged from a series of now classic studies that used tracers such as dextran, peroxidase, and ferritin to evaluate the influence of molecular charge on glomerular
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