Open AccessToward a Mouse Model of Diabetic Nephropathy
Author(s) -
Susan E. Quaggin,
Thomas M. Coffman
Publication year - 2007
Publication title -
journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.451
H-Index - 279
eISSN - 1533-3450
pISSN - 1046-6673
DOI - 10.1681/asn.2006121396
Subject(s) - diabetic nephropathy , diabetes mellitus , medicine , nephropathy , proteinuria , renal function , disease , kidney disease , kidney , renal pathology , endocrinology , pathology , bioinformatics , biology
Two articles in the October and February issues of JASN reported that diabetic mice that lack the eNOS gene develop accelerated kidney disease with features that resemble human diabetic nephropathy (DN). These articles are significant given the lack of good mouse models to study this important
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