Open AccessMEK Inhibition Holds Promise for Polycystic Kidney Disease
Author(s) -
James P. Calvet
Publication year - 2006
Publication title -
journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.451
H-Index - 279
eISSN - 1533-3450
pISSN - 1046-6673
DOI - 10.1681/asn.2006040353
Subject(s) - polycystic kidney disease , polycystic kidney , medicine , kidney disease , endocrinology , kidney , urology
Polycystic kidney disease (PKD) has a number of characteristics that make it uniquely challenging for the development of therapies to slow disease progression. Renal cystic diseases result from the neoplastic growth of numerous fluid-filled cysts, often accompanied by increased apoptosis, tissue
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