Open AccessScreening for ALK Rearrangements in Lung Cancer: Time for a New Generation of Diagnostics?
Author(s) -
DagogoJack Ibiayi,
Shaw Alice T.
Publication year - 2016
Publication title -
the oncologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.176
H-Index - 164
eISSN - 1549-490X
pISSN - 1083-7159
DOI - 10.1634/theoncologist.2016-0179
Subject(s) - medicine , genotyping , lung cancer , molecular diagnostics , dna sequencing , oncology , computational biology , companion diagnostic , cancer , medical physics , bioinformatics , genotype , genetics , gene , biology
A study reported in this issue of The Oncologist examined the utility of next‐generation sequencing (NGS) in detecting ALK rearrangements. NGS may one day become the standard initial test for molecular genotyping of patients with advanced cancers, and this new generation of ALK diagnostics is a welcome addition to the current screening repertoire.