Open AccessManagement of Localized Esophageal Cancer in the Older Patient
Author(s) -
Won Elizabeth,
Ilson David H.
Publication year - 2014
Publication title -
the oncologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.176
H-Index - 164
eISSN - 1549-490X
pISSN - 1083-7159
DOI - 10.1634/theoncologist.2013-0178
Subject(s) - medicine , esophageal cancer , chemoradiotherapy , cancer , intensive care medicine , population , population ageing , treatment modality , surgery , environmental health
Most patients with gastroesophageal cancers are older than 65 years of age. The management of older patients poses challenges because they have multiple comorbidities and physiological changes associated with aging. Furthermore, data are limited on tolerance of cancer therapy and the use of combined‐modality treatments in this patient population to guide their treatment. In this article, we focus on the management of older patients with localized esophageal cancer, highlighting the role of comprehensive geriatric assessment to identify and better tailor treatment approaches in this patient population. We review the literature and discuss the role of surgical resection and potential complications specific to an older patient. We review the rationale of combined‐modality treatment and the potential benefits of a chemoradiotherapy‐based approach in this patient population.