Open AccessPTEN Germline Mutations in Patients Initially Tested for Other Hereditary Cancer Syndromes: Would Use of Risk Assessment Tools Reduce Genetic Testing?
Author(s) -
Mester Jessica L.,
Moore Rebekah A.,
Eng Charis
Publication year - 2013
Publication title -
the oncologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.176
H-Index - 164
eISSN - 1549-490X
pISSN - 1083-7159
DOI - 10.1634/theoncologist.2013-0174
Subject(s) - medicine , pten , genetic testing , germline , germline mutation , cowden syndrome , hereditary cancer , cancer , mutation , cancer genetics , genetics , bioinformatics , oncology , gene , breast cancer , pi3k/akt/mtor pathway , biology , apoptosis
Learning ObjectivesCite the risk assessment tools available for several hereditary cancer predisposition syndromes. Describe ways in which use of these risk assessment tools can lead to cost savings and decreased time to correct diagnosis. Explain the impact of correct genetic diagnosis on the patient's medical management and on predictive testing for family members.