
IDH1 Gene Mutations: A New Paradigm in Glioma Prognosis and Therapy?
Author(s) -
Labussiere Marianne,
Sanson Marc,
Idbaih Ahmed,
Delattre JeanYves
Publication year - 2010
Publication title -
the oncologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.176
H-Index - 164
eISSN - 1549-490X
pISSN - 1083-7159
DOI - 10.1634/theoncologist.2009-0218
Subject(s) - medicine , idh1 , glioma , genetic enhancement , gene , oncology , targeted therapy , bioinformatics , mutation , cancer research , genetics , cancer , biology
The manuscript examines the role of isocitrate dehydrogenase 1 and the IDH1 gene in the prognosis and therapy of glial tumors.