Open AccessPrognosis and Prognostic Factors of the Micropapillary Pattern in Patients Treated for Stage II and III Serous Borderline Tumors of the Ovary
Author(s) -
Uzan Catherine,
Kane Aminata,
Rey Annie,
Gouy Sebastien,
Camatte Sophie,
Pautier Patricia,
Lhommé Catherine,
HaieMeder Christine,
Duvillard Pierre,
Morice Philippe
Publication year - 2011
Publication title -
the oncologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.176
H-Index - 164
eISSN - 1549-490X
pISSN - 1083-7159
DOI - 10.1634/theoncologist.2009-0139
Subject(s) - medicine , serous fluid , stage (stratigraphy) , conservative treatment , surgery , ovary , overall survival , survival rate , gastroenterology , paleontology , biology
Learning Objectives After completing this course, the reader will be able to: Discuss the prognostic impact of a micropapillary pattern in patients with stage II and III serous borderline ovarian tumors (SBOT). Consider when conservative surgery is an appropriate intervention in patients with SBOT‐MP.This article is available for continuing medical education credit at CME.TheOncologist.comBackground. To determine the prognosis of a micropapillary (MP) pattern in patients with stage II and stage III serous borderline tumor of the ovary (SBOT). Methods. Review of patients with stage II and stage III SBOT treated or referred to our institution with characterization of an MP pattern and its clinical impact. Results. In 1969–2006, 168 patients were reviewed. Fifty‐six patients had SBOT‐MP. The rate of conservative surgery was lower in the SBOT‐MP group than in the typical SBOT group, but the rate of patients with more than three peritoneal sites with implants was higher in the SBOT‐MP group. The rate of invasive implants was not statistically different between the two groups. Eighteen recurrences were observed (six of them in the form of invasive disease) in the SBOT‐MP group. Only one death was observed. The overall survival times and recurrence‐free intervals were similar in both groups. The only prognostic factor for recurrence in the SBOT‐MP group was the use of conservative surgery. Conclusions. In the present series, an MP pattern doesn't appear to signify a poor prognosis. The only prognostic factor for recurrence in SBOT‐MP was the use of conservative surgery. Further studies on the MP pattern are needed to evaluate prognosis and the results of conservative surgery.