Open AccessMalignancy in Children with Trisomy 21
Author(s) -
Rabin Karen R.,
Whitlock James A.
Publication year - 2009
Publication title -
the oncologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.176
H-Index - 164
eISSN - 1549-490X
pISSN - 1083-7159
DOI - 10.1634/theoncologist.2008-0217
Subject(s) - medicine , down syndrome , malignancy , trisomy , acute megakaryoblastic leukemia , lymphoblastic leukemia , disease , leukemia , pediatrics , oncology , intensive care medicine , genetics , psychiatry , biology
Learning ObjectivesEvaluate malignancies for which children with Down syndrome are at increased and decreased risk in order to screen appropriately. Analyze the clinical and biologic features of transient myeloproliferative disease and acute megakaryoblastic leukemia in children with DS. Determine the clinical and biologic features of acute lymphoblastic leukemia in children with DS and outline treatment strategies.This article is available for continuing medical education credit at CME.TheOncologist.com .