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Structural insights into regulation of nuclear receptors by ligands
Author(s) -
H. Eric Xu,
Millard H. Lambert
Publication year - 2003
Publication title -
nuclear receptor signaling
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.434
H-Index - 33
ISSN - 1550-7629
DOI - 10.1621/nrs.01004
Subject(s) - pelp 1 , nuclear receptor , transcription factor , receptor , computational biology , transcription (linguistics) , dna , biology , function (biology) , binding site , bioinformatics , microbiology and biotechnology , genetics , gene , linguistics , philosophy
Nuclear receptors are DNA-binding transcription factors, the transcriptional function of many of which depends on the binding of ligands, a feature that distinguishes nuclear receptors from other transcription factors. This review will summarize recent advances in our knowledge of the interaction between selected nuclear receptors and their cognate ligands.

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