Myoepithelioma of hard palate: A case report

Myoepitheliomas (ME) are benign neoplasm originating from myoepithelial cells of seromucinous glands. Majority of these tumours arise in parotid gland followed by minor salivary glands of palate. The tumor does not show any unique clinicopathologic features that is different from other benign salivary gland tumors but is believed to have more aggressive behaviour. The histopathological patterns vary to very great extent and usually show overlapping features with other benign and malignant tumours. We report a case of 38-year-old male patient with a solitary swelling present on the right side of the hard palate. The histopathologic picture of the lesion showed spindle, plamacytoid and epitheliod cells. The connective stroma showed areas of hyalinization and keratin pearl formation making it difficult to differentiate from pleomorphic adenoma as well as its malignant counterpart. An Immunohistochemical analysis was done using S100, smooth muscle actin, Ki-67 and a definitive diagnosis of ME was made.