Targeted therapy for oral submucous fibrosis - Future strategies

This editorial is with the objective of igniting the research minds of the specialists treating “oral submucous fibrosis (OSMF),” a chronic debilitating and potentially malignant condition of the oral cavity. Though the etiology of OSMF is multifactorial, the most accepted pathway of pathogenesis is dysregulation of collagen synthesis and degradation pathway[1] similar to many other fibrosing conditions explored in the medical literature. This study sketches some of the successful trials that can possibly help in the successful management of advanced cases.