Porphyria cutanea tarda - A case report

Porphyria was first described in literature by Waldenstrom in 1937. It is a metabolic disorder that results due to decrease in uroporphyrinogen decarboxylase (URDO) activity, clinically characterized by blisters, photosensitivity, and hyperpigmented macule in sun-exposed area.[1] There are seven main types of porphyria; they are broadly classified according to clinical features into neuropsychiatric, dermatological, and mixed forms. Acute intermittent porphyria and plumboporphyria are predominantly neuropsychiatric; congenital erythropoietic porphyria, porphyria cutanea tarda (PCT), and erythropoietic protoporphyria have predominantly cutaneous manifestations, and variegate porphyria is classified as mixed as they have both cutaneous and neuropsychiatric features.