Evaluation of efficacy of indigenously prepared formulation of Aloe vera, licorice and sesame oil in treatment of oral lichen planus: An in vivo study

Background: Oral lichen planus (OLP) is a chronic mucocutaneous inflammatory disease characterized by eruptions on the skin and oral mucous membranes. Various therapies have been tried for the treatment of lichen planus with varying results. Aloe barbadensis, Aloe capensis is scientific name for Aloe vera (AV). AV is a very versatile plant that has many different uses. AV is a promising herb with its various clinical applications in medicine and dentistry. Objectives: To assess decrease in pain, burning sensation, erythema, functional disturbances and recurrence in patients diagnosed with lichen planus treated with the prepared formulation of AV and licorice and sesame oil. Materials and Methods: A total of 30 adult patients who came to Dr. D.Y. Patil Dental College and Hospital, Pimpri, Pune and were diagnosed with OLP were included in the study. Each patient was administered 50 ml prepared formulation of AV and licorice and sesame oil in the form of a gargle which was swished for a minimum of 5 min in the oral cavity twice daily for a period of 6-week. Results: After evaluation with Tukey’s test and Wincoxin test it was found that there is a decrease in pain, erythema, burning sensation, functional disturbance after using prepared formulation.