Drug-induced gingival enlargement in a hypertensive patient with chronic smoking behavior - A case report

Drug-induced gingival enlargement is often observed as a side effect of some pharmacologic agents which might have been prescribed for non-dental reasons, for which the gingival tissue is not the intended target. These medications mainly include antihypertensives, anticonvulsants, and immunosuppressants class of drugs. Here, we describe a case of amlodipine-induced massive gingival enlargement in a 40-year-old male patient with chronic smoking habit. The patient was advised regarding the gingival enlargement and its probable cause. His family physician was consulted, who substituted an angiotensin receptor blocker for the amlodipine. He was further counseled for tobacco cessation, instructed on good oral hygiene techniques, and advised for a surgical periodontal treatment.