Pyogenic granuloma of oral cavity: Case series and clinicopathologic correlation

Background: Pyogenic granuloma is an inflammatory hyperplasia occasionally observed in the oral cavity. The term pyogenic granuloma is a misnomer because it neither contains pus nor it is a granuloma histologically. Most commonly occurs in the second decade of life and females are more commonly affected. Trauma, calculus, pregnancy, hormonal factors are the common etiological factors associated. It appears as smooth or lobulated exophytic lesion, mostly pedunculated and bleeds on slight probing. The diagnosis of pyogenic granuloma should be confirmed by histopathology and treatment of choice is surgical excision. Recurrence is not uncommon and mainly occurs due to incomplete excision and persisting etiology. Aim: This article presents four cases of oral pyogenic granuloma with literature review summarizing the existing knowledge of etiopathogenesis, diagnosis and management of this non neoplastic lesion. Conclusion: Pyogenic granuloma occurs as mostly painless benign growth but causes great discomfort and fear of malignancy to the patient. Surgical excision and removal of etiological factors are the mainstay treatment. Clinical Significance: This article reiterates importance of correct diagnosis and treatment planning in common oral lesions such as pyogenic granuloma. Histopathological examination of the excised lesion can help in definitive diagnosis. Pyogenic granuloma bleeds profusely and hence adequate hemostatic measures should be employed during and after the surgery.