Advanced injectable scaffold system signpost for development in endodontic tissue regeneration

Commentary: Tissue engineering is a reassuring approach for dentin-pulpal complex regeneration. Tissue regeneration consists of three factors: stem cells, growth factors, and scaffolds. The scaffold is an artificial extracellular matrix (ECM) which serves as a template for cell growth and tissue regeneration1. Required properties of scaffolds are they ought to be biocompatible, biodegradable, have specific physical and mechanical properties, and have to mimic the in-vivo environment. According to shape, scaffolds are of two types: preformed scaffolds and injectable scaffolds. Preformed scaffolds have the previous form whereas injectable scaffolds can be injected into destined space and form shape of in situ structure2. Considering tiny form and size of the root canals injectable scaffolds are additionally appealing than that of preformed ones in endodontics3. Recently certain bio-inductive materials are added into synthetic scaffolds for obtaining superior outcomes.