Comparison of Efficiency between Pre-storage and Post-storage filtration by Leukoreduction Blood Filter | Zendy

Geon Sik Shin | Zendy; Bohee Kim | Zendy; Sung Hoon Kim | Zendy; KiJong Rhee | Zendy; Yoon Suk Kim | Zendy

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Comparison of Efficiency between Pre-storage and Post-storage filtration by Leukoreduction Blood Filter

Author(s) -

Geon Sik Shin,

Bohee Kim,

Sung Hoon Kim,

KiJong Rhee,

Yoon Suk Kim

Publication year - 2017

Publication title -

journal of experimental and biomedical sciences/biomedical science letters

Language(s) - English

Resource type - Journals

eISSN - 2288-7415

pISSN - 1738-3226

DOI - 10.15616/bsl.2017.23.2.111

Subject(s) - leukoreduction , filtration (mathematics) , hemolysis , chemistry , chromatography , blood transfusion , medicine , surgery , immunology , mathematics , statistics

Leukocytes in blood components are involved in diverse adverse transfusion reactions such as febrile non-hemolytic transfusion reactions. Therefore, leukocyte reduction is required to reduce these adverse reactions. The objective of this study was to compare the efficiency of pre-storage filtration and post-storage filtration. Filtration time, residual leukocyte count, RBC recovery, and hemolysis were assessed after pre-storage or post-storage filtration. Compared to pre-storage filtration, filtration time was prolonged and hemolysis was dramatically increased when post-storage filtration was performed. Residual leukocytes count and RBC recovery after post-storage filtration were similar with those obtained after pre-storage filtration. These results suggest that pre-storage filtration has better efficiency than post-storage filtration. These are thought to contribute to the production of better quality of leukoreduction blood components.

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