Mikroszatellita-instabilitás előfordulása, intratumoralis heterogenitása, prognosztikus és prediktív potenciálja primer colorectalis carcinomák és párosított májáttéteik sebészi kezelését követően
Author(s) -
Emese Irma Ágoston,
Zsolt Baranyai,
Kristóf Dede,
G. Bodoky,
Janina Kulka,
Attila Bursics,
László Harsányi,
Attila Marcell Szász
Publication year - 2015
Publication title -
orvosi hetilap
Language(s) - Hungarian
Resource type - Journals
SCImago Journal Rank - 0.176
H-Index - 21
eISSN - 1788-6120
pISSN - 0030-6002
DOI - 10.1556/650.2015.30218
Subject(s) - msh6 , microsatellite instability , msh2 , pms2 , mlh1 , medicine , oncology , colorectal cancer , predictive marker , lynch syndrome , dna mismatch repair , gastroenterology , biology , cancer , microsatellite , genetics , allele , gene
Besides clinicopathological parameters, molecular markers can be very important, and further characterize colorectal carcinomas into chromosomally unstable, microsatellite instable and "CqG-island methylator phenotype" groups.
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