COMPARISON OF MATHEMATICAL MODELS FOR THE USE OF ENROFLOXACIN IN DOGS | Zendy

Miroslav Vasilev | Zendy; Galya Shivacheva | Zendy

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COMPARISON OF MATHEMATICAL MODELS FOR THE USE OF ENROFLOXACIN IN DOGS

Author(s) -

Miroslav Vasilev,

Galya Shivacheva

Publication year - 2019

Publication title -

applied researches in technics technologies and education

Language(s) - English

Resource type - Journals

eISSN - 1314-8796

pISSN - 1314-8788

DOI - 10.15547/artte.2019.02.004

Subject(s) - akaike information criterion , enrofloxacin , mathematics , ordinary differential equation , differential equation , differential (mechanical device) , process (computing) , statistics , mathematical analysis , computer science , chemistry , thermodynamics , physics , antibiotics , biochemistry , ciprofloxacin , operating system

This article analyzes the process of changing the concentration of enrofloxacin in blood plasma in dogs after a single intravenous injection of the substance. Three mathematical models are proposed algebraic and two models, based on a differential equation of first and second order. Identification of their parameters has been performed. Based on Akaike information criterion corrected as the best model was chosen the represented by a second-order differential equation. Three equations are identified and the exact numerical values of their parameters are obtained. For the evaluation and comparison of the three models, Akaike information criterion was used. The best results showed the second-order differential model. It will be used in future developments.

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