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the Irradiation of Two Cases of Gliosarcoma: Place and Modalities of Radiotherapy
Author(s) -
Rajae En Nouichi,
Ghita Chbihi Hassani,
Fadwa Allouche,
M. Ait Erraisse,
Z. Alami,
Fz. Farhane,
Pr. T. Bouhafa,
Pr. K. Hassouni
Publication year - 2020
Publication title -
journal of medical biomedical and applied sciences
Language(s) - English
Resource type - Journals
ISSN - 2349-0748
DOI - 10.15520/jmbas.v8i6.232
Subject(s) - gliosarcoma , glioblastoma , parenchyma , radiation therapy , medicine , chemotherapy , pathology , radiology , cancer research
Gliosarcoma is a rare histopathologic variant of glioblastoma traditionally associated with a poor prognosis.We present two cases of Gliosarcoma treated in our department. Discussion: Gliosarcoma (GSM) is a variant of glioblastoma (GBM), the most common primary malignant brain tumor that occurs in adults. GSM is characterized by its biphasic components: the gliomatous and sarcomatous components and categorized into primary and secondary GSM. Intrinsic to the brain parenchyma, GSM is usually managed by gross total resection, and radiotherapy with/without chemotherapy. Conclusion: Despite the notable advances and improvement in overall survival (OS), a consensus on the optimal treatment for GSM patients is unclear.

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