Pathophysiology and Therapeutic Control of Coronary Artery Restenosis

Coronary artery restenosis is an occlusive vascular response to arterial injury and inflammation that often occurs after surgical interventions for cardiovascular disease. Extensive studies have been done to understand the pathophysiology of restenosis and therefore figure out the solutions to this problem. In this review, we attempt to summarize the physiological roles of the main constituents in coronary artery and their relation to the pathophysiology of restenosis. We also discuss current clinical therapeutic measures to prevent restenosis and the efforts made in the research to improve the performance of implanted devices for cardiovascular disease treatment.■