Open AccessA Conserved NRDE-2/MTR-4 Complex Mediates Nuclear RNAi in Caenorhabditis elegans
Author(s) -
Gang Wan,
Jenny Yan,
Yuhan Fei,
Daniel J. Pagano,
Scott Kennedy
Publication year - 2020
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1534/genetics.120.303631
Subject(s) - caenorhabditis elegans , biology , rna interference , genetics , rna splicing , genome , caenorhabditis , argonaute , microbiology and biotechnology , computational biology , gene , rna
Small regulatory RNAs such as siRNAs regulate splicing, transcription, and genome integrity in many eukaryotes. In Caenorhabditis elegans, siRNAs bind nuclear Argonautes, which interact with homologous
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