Simultaneous Discovery of Cell-Free DNA and the Nucleosome Ladder
Author(s) -
Steven Henikoff,
George M. Church
Publication year - 2018
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1534/genetics.118.300775
Subject(s) - biology , nucleosome , genetics , dna , computational biology , histone
u003e A remarkably prescient paper published by Robert Williamson in 1970 was the first description and correct interpretation of both the apoptotic origin of cell-free DNA and the subunit structure of chromatin. Thus, the original observation that forms the basis for this powerful precision medicine
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