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![][1] By the early 1920s, the existence of mutations was well established, but how they could be generated remained a topic of lively speculation. One interesting case was the Drosophila Bar mutation ([Tice 1914][2]). While normal flies have round eyes, the X-linked mutation Bar ( B

Alfred Sturtevant Walks into a Bar: Gene Dosage, Gene Position, and Unequal Crossing Over in Drosophila