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Location Is Everything: An Educational Primer for Use with “Genetic Analysis of the Ribosome Biogenesis Factor Ltv1 of Saccharomyces cerevisiae
Author(s) -
Gretchen Edwalds-Gilbert
Publication year - 2015
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1534/genetics.114.173641
Subject(s) - ribosome biogenesis , genetics , biology , ribosome , biogenesis , saccharomyces cerevisiae , ribosomal protein , ribosomal rna , computational biology , primer (cosmetics) , gene , rna , physics , thermodynamics
The article by Merwin et al. in the November 2014 issue of GENETICS provides insight into ribosome biogenesis, an essential multistep process that involves myriad factors and three cellular compartments. The specific protein of interest in this study is low-temperature viability protein (Ltv1), which functions as a small ribosomal subunit maturation factor. The authors investigated its possible additional function in small-subunit nuclear export. This Primer provides information for students to help them analyze the paper by Merwin et al. (2014), including an overview of the authors' research question and methods.

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