Open AccessRNA-Guided Nucleases: A New Era for Engineering the Genomes of Model and Nonmodel Organisms
Author(s) -
Kent G. Golic
Publication year - 2013
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1534/genetics.113.155093
Subject(s) - biology , genome , genetics , rna , genome engineering , computational biology , evolutionary biology , gene , genome editing
In 1946, H. J. Muller was awarded the Nobel Prize in Medicine for his discovery with Drosophila melanogaster , some 20 years earlier, that exposure to X-rays caused mutation ([Muller 1927][1]). This led to the identification of a large number of Drosophila mutants and chromosome rearrangements, many
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