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Asexuals, Polyploids, Evolutionary Opportunists...: The Population Genetics of Positive but Deteriorating Mutations
Author(s) -
Bengt Bengtsson
Publication year - 2012
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1534/genetics.112.140715
Subject(s) - biology , genetics , fixation (population genetics) , mutation , population , selection (genetic algorithm) , mutation accumulation , positive selection , population genetics , evolutionary biology , mutation rate , gene , demography , artificial intelligence , sociology , computer science
Some genetic phenomena originate as mutations that are initially advantageous but decline in fitness until they become distinctly deleterious. Here I give the condition for a mutation-selection balance to form and describe some of the properties of the resulting equilibrium population. A characterization is also given of the fixation probabilities for such mutations.

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