Everything You Ever Wanted to Know About Saccharomyces cerevisiae Telomeres: Beginning to End | Zendy

Raymund J. Wellinger | Zendy; Virginia A. Zakian | Zendy

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Everything You Ever Wanted to Know About Saccharomyces cerevisiae Telomeres: Beginning to End

Author(s) -

Raymund J. Wellinger,

Virginia A. Zakian

Publication year - 2012

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1534/genetics.111.137851

Subject(s) - telomere , biology , saccharomyces cerevisiae , genetics , budding yeast , telomerase , yeast , genome , homologous recombination , organism , model organism , dna , gene

The mechanisms that maintain the stability of chromosome ends have broad impact on genome integrity in all eukaryotes. Budding yeast is a premier organism for telomere studies. Many fundamental concepts of telomere and telomerase function were first established in yeast and then extended to other organisms. We present a comprehensive review of yeast telomere biology that covers capping, replication, recombination, and transcription. We think of it as yeast telomeres--soup to nuts.

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