Extended Linkage Disequilibrium in Noncoding Regions in a Conifer, Cryptomeria japonica
Author(s) -
Etsuko Moritsuka,
Yosuke Hisataka,
Miho Tamura,
Kentaro Uchiyama,
Atsushi Watanabe,
Yoshihiko Tsumura,
Hidenori Tachida
Publication year - 2011
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1534/genetics.111.136697
Subject(s) - cryptomeria , biology , linkage disequilibrium , genetics , japonica , disequilibrium , linkage (software) , evolutionary biology , haplotype , botany , allele , gene , medicine , ophthalmology
We measured linkage disequilibrium in mostly noncoding regions of Cryptomeria japonica, a conifer belonging to Cupressaceae. Linkage disequilibrium was extensive and did not decay even at a distance of 100 kb. The average estimate of the population recombination rate per base pair was 1.55 × 10(-5) and was <1/70 of that in the coding regions. We discuss the impact of low recombination rates in a large part of the genome on association studies.
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