Chromatin and Transcription in Yeast | Zendy

Oliver J. Rando | Zendy; Fred Winston | Zendy

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Chromatin and Transcription in Yeast

Author(s) -

Oliver J. Rando,

Fred Winston

Publication year - 2012

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1534/genetics.111.132266

Subject(s) - chromatin , biology , histone , saccharomyces cerevisiae , histone modifying enzymes , chromatin remodeling , genetics , transcription (linguistics) , bivalent chromatin , yeast , chia pet , transcription coregulator , computational biology , microbiology and biotechnology , gene , linguistics , philosophy

Understanding the mechanisms by which chromatin structure controls eukaryotic transcription has been an intense area of investigation for the past 25 years. Many of the key discoveries that created the foundation for this field came from studies of Saccharomyces cerevisiae, including the discovery of the role of chromatin in transcriptional silencing, as well as the discovery of chromatin-remodeling factors and histone modification activities. Since that time, studies in yeast have continued to contribute in leading ways. This review article summarizes the large body of yeast studies in this field.

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