Parallel Evolution of Bacillus thuringiensis Toxin Resistance in Lepidoptera
Author(s) -
Simon W. Baxter,
Francisco Rubén BadenesPérez,
Anna Morrison,
Heiko Vogel,
Neil Crickmore,
Wendy Kain,
Ping Wang,
David G. Heckel,
Chris D. Jiggins
Publication year - 2011
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1534/genetics.111.130971
Subject(s) - bacillus thuringiensis , cry1ac , biology , lepidoptera genitalia , toxin , genetics , agricultural pest , locus (genetics) , bacillaceae , bacillales , resistance (ecology) , genetically modified crops , gene , microbiology and biotechnology , bacteria , botany , transgene , ecology , bacillus subtilis , agricultural science
Despite the prominent and worldwide use of Bacillus thuringiensis (Bt) insecticidal toxins in agriculture, knowledge of the mechanism by which they kill pests remains incomplete. Here we report genetic mapping of a membrane transporter (ABCC2) to a locus controlling Bt Cry1Ac toxin resistance in two lepidopterans, implying that this protein plays a critical role in Bt function.
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