Trans-Centromere Effects on Meiotic Recombination in the Zebrafish
Author(s) -
Bradley L. Demarest,
Wyatt Horsley,
Erin E Locke,
Kenneth M. Boucher,
David J. Grunwald,
Nikolaus S. Trede
Publication year - 2010
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1534/genetics.110.124081
Subject(s) - centromere , biology , genetics , meiosis , recombination , homologous recombination , zebrafish , meiotic drive , chromosome , gene
We report that lack of crossover along one chromosome arm is associated with high-frequency occurrence of recombination close to the opposing arm's centromere during zebrafish meiotic recombination. Our data indicate that recombination behavior on the two arms of a chromosome is linked. These results inform mapping strategies for telomeric mutants.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom