Identification of New Quantitative Trait Loci (Other Than the PRNP Gene) Modulating the Scrapie Incubation Period in Sheep | Zendy

Carole Moréno | Zendy; Gian Mario Cosseddu | Zendy; Laurent Schibler | Zendy; Antoni Roig | Zendy; Katayoun MoazamiGoudarzi | Zendy; Olivier Andréoletti | Zendy; Francis Eychenne | Zendy; Daniel Lajous | Zendy; F. Schelcher | Zendy; E.P. Cribiu | Zendy; P. Laurent | Zendy; Daniel Vaiman | Zendy; Jean-Michel Elsen | Zendy

Open Access

Identification of New Quantitative Trait Loci (Other Than the PRNP Gene) Modulating the Scrapie Incubation Period in Sheep

Author(s) -

Carole Moréno,

Gian Mario Cosseddu,

Laurent Schibler,

Antoni Roig,

Katayoun MoazamiGoudarzi,

Olivier Andréoletti,

Francis Eychenne,

Daniel Lajous,

F. Schelcher,

E.P. Cribiu,

P. Laurent,

Daniel Vaiman,

Jean-Michel Elsen

Publication year - 2008

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1534/genetics.108.088146

Subject(s) - scrapie , biology , prnp , incubation period , genotype , genetics , trait , gene , quantitative trait locus , incubation , virology , phenotype , prion protein , disease , medicine , biochemistry , pathology , computer science , programming language

Although susceptibility to scrapie is largely controlled by the PRNP gene, we have searched for additional genomic regions that affect scrapie incubation time in sheep, using two half-sib families with a susceptible PRNP genotype and naturally infected by scrapie. Quantitative trait loci were detected on OAR6 and OAR18.

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