Drosophila G9a Is a Nonessential Gene | Zendy

Carole Seum | Zendy; Séverine Bontron | Zendy; Emanuela Reo | Zendy; Marion Delattre | Zendy; Pierre Spierer | Zendy

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Drosophila G9a Is a Nonessential Gene

Author(s) -

Carole Seum,

Séverine Bontron,

Emanuela Reo,

Marion Delattre,

Pierre Spierer

Publication year - 2007

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1534/genetics.107.078220

Subject(s) - biology , genetics , allele , euchromatin , gene , histone methyltransferase , drosophila (subgenus) , methyltransferase , homologous recombination , drosophila melanogaster , homologous chromosome , heterochromatin protein 1 , histone , heterochromatin , chromatin , methylation

Mammalian G9a is a euchromatic histone H3 lysine 9 (H3K9) methyltransferase essential for development. Here, we characterize the Drosophila homolog of G9a, dG9a. We generated a dG9a deletion allele by homologous recombination. Analysis of this allele revealed that, in contrast to recent findings, dG9a is not required for fly viability.

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