Genetic Dissection of Cytonuclear Epistasis in Line Crosses | Zendy

Zaixiang Tang | Zendy; Xuefeng Wang | Zendy; Zhiqiu Hu | Zendy; Zefeng Yang | Zendy; Chenwu Xu | Zendy

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Genetic Dissection of Cytonuclear Epistasis in Line Crosses

Author(s) -

Zaixiang Tang,

Xuefeng Wang,

Zhiqiu Hu,

Zefeng Yang,

Chenwu Xu

Publication year - 2007

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1534/genetics.107.074302

Subject(s) - epistasis , biology , genetics , genetic architecture , quantitative trait locus , phenotype , evolutionary biology , computational biology , gene

Dissection of cytonuclear interactions is fundamentally important for understanding the genetic architecture of complex traits. Here we propose a mating design based on reciprocal crosses and extend the existing QTL mapping method to evaluate the contribution of cytoplasm and QTL x cytoplasm interactions to the phenotypic variation. Efficiency of the design and method is demonstrated via simulated data.

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