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Two-Locus Epistasis With Sexually Antagonistic Selection: A Genetic Parrondo's Paradox
Author(s) -
Floyd A. Reed
Publication year - 2007
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1534/genetics.106.069997
Subject(s) - epistasis , biology , allele , genetics , locus (genetics) , fixation (population genetics) , population , selection (genetic algorithm) , allele frequency , evolutionary biology , gene , demography , artificial intelligence , sociology , computer science
An example is provided where, with antagonistic selection and epistatic interaction of alleles at two loci, an autosomal allele can rise in frequency, persist in the population, and even continue to fixation, despite having an apparently lower average fitness than the alternative allele, in a process similar to Parrondo's paradox.

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