Open AccessSmg1 Nonsense Mutations Do Not Abolish Nonsense-Mediated mRNA Decay in Drosophila melanogaster
Author(s) -
Zhenzhong Chen,
Katherine R. Smith,
Philip Batterham,
Charles Robin
Publication year - 2005
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1534/genetics.105.045674
Subject(s) - nonsense mediated decay , biology , drosophila melanogaster , nonsense , genetics , nonsense mutation , mutation , gene , rna , missense mutation , rna splicing
Smg1 is a key component of nonsense-mediated decay (NMD) in Caenorhabditis elegans and mammals. Here we report that two nonsense alleles of the ortholog of Smg1 do not affect NMD in Drosophila melanogaster.
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