Open AccessExtending Xu's Bayesian Model for Estimating Polygenic Effects Using Markers of the Entire Genome
Author(s) -
Cajo J. F. ter Braak,
Martin P. Boer,
M.C.A.M. Bink
Publication year - 2005
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1534/genetics.105.040469
Subject(s) - biology , genetics , bayesian probability , genome , computational biology , evolutionary biology , gene , statistics , mathematics
In 2003, Xu obtained remarkably precise estimates of QTL positions despite the many markers simultaneously in his Bayesian model. We extend his model and Gibbs algorithm to ensure a valid posterior distribution and convergence to it, without changing the attractiveness of the method.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom