Open AccessUpdate on Estimation of Mutation Rates Using Data From Fluctuation Experiments
Author(s) -
Qi Zheng
Publication year - 2005
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1534/genetics.104.035774
Subject(s) - mutation rate , mutation , biology , estimation , genetics , remedial education , computational biology , mathematics , gene , engineering , mathematics education , systems engineering
This note discusses a minor mathematical error and a problematic mathematical assumption in Luria and Delbrück's (1943) classic article on fluctuation analysis. In addition to suggesting remedial measures, the note provides information on the latest development of techniques for estimating mutation rates using data from fluctuation experiments.
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