Many P-Element Insertions Affect Wing Shape in Drosophila melanogaster
Author(s) -
Kenneth Weber,
Nancy Johnson,
David T. Champlin,
April Patty
Publication year - 2004
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1534/genetics.104.027748
Subject(s) - wing , drosophila melanogaster , biology , genetics , melanogaster , genome , p element , drosophila (subgenus) , drosophilidae , gene , engineering , aerospace engineering
A screen of random, autosomal, homozygous-viable P-element insertions in D. melanogaster found small effects on wing shape in 11 of 50 lines. The effects were due to single insertions and remained stable and significant for over 5 years, in repeated, high-resolution measurements. All 11 insertions were within or near protein-coding transcription units, none of which were previously known to affect wing shape. Many sites in the genome can affect wing shape.
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